Resetarits began his indoor lacrosse career with the St. Catharines Athletics, and joined the Brampton Excelsiors in 2011, with whom he won the Mann Cup in that same year.

He was drafted 6th overall by the Calgary Roughnecks in the 2012 NLL Entry Draft. Although he received All Rookie honors, scoring 8 goals and 24 points, his Roughnecks team led the league in scoring and featured seven players who recorded at least 25 points. Resetarits was deemed expendable by the Roughnecks, and was traded to his hometown Buffalo Bandits during the 2013 NLL Entry Draft. Resetarits played for the Bandits for 2 seasons before being traded to Rochester in 2015 where he enjoyed 4 great seasons, the last of which he reached the 100 point milestone for the first time in his NLL career. Resetarits also made a stop in Albany before joining the Philadelphia Wings in 2023.

Heading into the 2023 NLL season, Inside Lacrosse ranked Resetarits the #3 best forward in the NLL. In December of the 2023 season Resetarits passed Casey Powell for Most Points by American in NLL History.

Resetarits has also added to his accolades in Major Series Lacrosse (MSL), Canada's Senior A Box Lacrosse League, as a Two-time Mann Cup Champion with the Peterborough Lakers. Joe is also a Three-Time medal winner at the indoor world games bringing home 2 Bronze Medals and 1 Silver Medal for Team USA.